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What causes breakthrough depression in bipolar disorder?


I've been on my present cocktail for more than 10 years now with few if any problems. Right now life is absolute hell--and believe me, I know clinical depression from the blahs--and I'm not sure why. I've got some outside stressors, but nothing unusual--so I'm wondering why now? What can I do about it anyway?

i found these sites.........

http://books.google.com/books?hl=en&lr=&...

http://linkinghub.elsevier.com/retrieve/...

http://cme.medscape.com/viewarticle/4701...

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